NEW WOMEN-ONLY BIO-AGE TEST ENDS THE DATA GAP

💪 Dear Wonderwomen and Supermen,

Did you know that most medical algorithms are trained on male data ?

This historical gap has led to delayed diagnoses and less accurate medicine for women. BASE4 Biosciences, a visionary startup, aims to change this with a blood test capable of estimating the biological age of more than 45 organs — trained exclusively on female data.

A world first. Imagine detecting early signs of decline even before symptoms appear. Intrigued ?

Read on to discover how this innovation could redefine preventive health for women.

SPOTLIGHT

BASE4 Biosciences, a spin-off from Barcelona’s Sant Pau Research Institute, is developing an unprecedented multi-omics blood test dedicated to women’s health. The goal : estimating the biological age of 45 organs by analyzing over 16,000 gene-expression signals from a simple sample. This test, based on AI models trained exclusively on female data, promises ultra-early detection of organ aging and molecular disruptions long before any clinical signs appear. The stakes are high: addressing the historical exclusion of women from biomedical research and finally personalizing preventive medicine for women.

The details :

• An algorithm designed for the female body : Unlike conventional tools built on male-dominant datasets, BASE4’s approach accounts for physiological transitions unique to women: menstruation, pregnancy, perimenopause, menopause. These events profoundly shape molecular trajectories, making specific modeling indispensable for reliable diagnostics.

• Ultra-early and reversible diagnostics : The test can identify early transcriptomic abnormalities before symptoms or visible lesions emerge. This anticipatory ability enables targeted interventions at a stage when damage is still reversible, maximizing the chances of long-term healthy longevity.

• A response to decades of medical inequality : BASE4 joins the fight against sex bias in medicine. Historically excluded from clinical trials, women face longer diagnostic delays and less effective treatments. By proposing a “Human Female Body Atlas,” the startup helps correct this data asymmetry.

• A concrete application for fertility : A second test is undergoing clinical validation to detect premature ovarian insufficiency — a major issue for women navigating fertility challenges. Its launch is expected in 2027, with commercialization through specialized clinics.

• A model inspired by a pioneer : Athlete and biochemist Emma Roca, whose work influenced the creation of BASE4, embodies the spirit of the project. Her death from a cancer diagnosed too late strengthened the team’s conviction: understanding female biological specificity is a medical imperative.

Key Takeaway :

BASE4 represents a new era of precision medicine for women. Through a multi-omics approach centered on the female body, it offers ultra-personalized prevention capable of detecting signs of organ aging before they become irreversible. This paradigm shift could reshape the way longevity is understood for women — finally making it visible, measurable, and above all, actionable.

HYPE OR FACT ?

💭 Multivitamins are essential for health at any age

❌ HYPE

Scientific research shows that generic multivitamins do not provide meaningful benefits for longevity or chronic disease prevention in healthy adults. A large study published in Annals of Internal Medicine (2019) found that these supplements did not improve cardiovascular health or reduce mortality. Worse, certain poorly dosed components — like iron or vitamin E — can even be harmful. Supplementation should therefore be targeted and based on biological analyses, not on standardized formulas.

LONGEVITY WISDOM

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